American Cruise Lines 2025 Schedule. American cruise lines said it will offer one of the longest river cruise packages ever sold in the u.s., spanning 51 days on three rivers on three ships. Destinations include florida, south carolina, new.

Since 1973, they have been known for the finest. American cruise lines offers an inclusive, immersive experience with the newest fleet in america, each ship accommodating just 90 to 170 guests.